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KMID : 0614620190730030152
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Korean Journal of Gastroenterology
2019 Volume.73 No. 3 p.152 ~ p.158
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Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study
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Kim Ji-Woo
Kim Su-Young
Choi Jung-Hye
Kim Hyun-Soo
Lee Jung-Kuk
Kim Yun-Tae
Park Geun-U
Kang Dae-Ryong
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Abstract
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Background/Aims: Despite the many reports of colonoscopy complications worldwide, few studies have been performed at the population level in Korea. In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group.
Methods: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. The clinical characteristics and perforation incidence (within 30 days after the colonoscopy) of cases were identified, and cases were then compared with controls who had not undergone a colonoscopy.
Results: Among 1,380,000 subjects, 31,177 cases and 62,354 controls were identified. Perforation occurred in 14 patients (0.04%) in the case group and one patient (<0.01%) in the control group (RR, 28.0; 95% CI 3.7?212.9, p<0.001). Subgroup analysis was followed according to the endoscopic procedure, gender and age. In subgroup analysis, colonoscopy-associated perforations occurred more in the therapeutic procedure (RR, 26; 95% CI 1.46?461.46), male (RR, 50; 95% CI 2.96?844.41), and age of 45?60 years (RR, 30; 95% CI 1.71?525.23).
Conclusions: A colonoscopy procedure is related to an increased risk of perforation at the population level. In addition, the therapeutic procedure, male, and age of 45-60 years appeared to be associated with an increased risk of perforation.
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KEYWORD
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Colonoscopy, Complications, Intestinal perforation
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